Tali Cukierman-Yaffe

Sheba Medical Center, Israel

Tali Cukierman-Yaffe is an endocrinologist and a clinical epidemiologist.  She is a senior physician in the Endocrinology Institute, the head of the Centre for Successful Aging with Diabetes in the Sheba Medical Centre, has a senior lecturer position in the Epidemiology department at the Sackler school of Medicine and is a member of the Herczeg Institute on Aging, Tel-Aviv University.  She is also  a PHRI (Population Health Research Institute, Mcmaster University, Canada) international fellow.

She has   extensive experience in epidemiological clinical studies in the area of cognition and diabetes.  She was the principal investigator (PI) of the cognitive sub-study of the ORIGIN trial (Outcome Reduction with Initial Glargine Intervention) a 12,500 person multi-center randomized controlled study that assessed the cognitive safety of Insulin Glargine. She was a co-investigator of the ACCORD-MIND study (Action to Control Cardiovascular Risk in Diabetes-Memory in Diabetes) a ~3000 person randomized controlled study that assessed the cognitive efficacy of tight vs. standard glucose control and took a lead role in determining which cognitive tools to use and how to analyze them.   She has a lead a key role in the cognitive part of the REWIND trial that  tested the cognitive safety and efficacy of Dulaglutide in people with diabetes.

She is a key opinion leader in the relationship between diabetes and cognitive dysfunction and the challenges of treating diabetes in older age.  She has given numerous talks on this topic, is part of working groups writing local and international guidelines on this topic and is an invited advisor in forums dealing with this subject.


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